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MHRA: Miconazole and warfarin

30/6/2016

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The MHRA has issued a warning about the risks of patients on warfarin taking miconazole-containing medicines (including  topicals)  in June 2016
  • Miconazole, including the topical gel formulation, can enhance the anticoagulant effect of warfarin—if miconazole and warfarin are used concurrently, the anticoagulant effect should be carefully monitored and, if necessary, the dose of warfarin reduced
Further information is available on the MHRA website.
MHRA advice to healthcare professionals
  • Patients should be advised to tell their doctor or pharmacist if they are receiving warfarin before using products that contain miconazole (including those available without prescription), and to seek medical advice if they notice signs of over-anticoagulation during treatment, such as sudden unexplained bruising, nosebleeds or blood in the urine
QMasters' tools to help GPs implement this guidance
Please download our free search to identify patients who are taking warfarin and miconazole.
​
You must right-click on this and select "Save As" and import the file into Population Reporting in EMIS Web.
miconazole_and_warfarin_last_month__v1.0___www.qmasters.co.uk_.xml
File Size: 4 kb
File Type: xml
Download File

​Please note our search relies on accurate clinical coding to identify these patients and we are unable to guarantee that all patients will be correctly identified.
GP practices subscribing to our QToolset will receive an automatic clinical safety pop-up warning with their next update. This warning will appear whenever miconazole is prescribed for a patient on warfarin.
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For more information about our QToolset and to learn how it will save GPs time, maximise income, and improve clinical safety please visit www.QMasters.co.uk/qtoolset.
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    These free searches are provided to help GP practices improve clinical safety. This page is updated regularly as new guidance is published.
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    QToolset subscribers also receive live monitoring of EMIS Web to ensure users are alerted immediately a potential clinical safety issue has been identified. These alerts have been rated as "outstanding" by CQC.

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